We are thrilled to announce our paper synthetic receptor mechanisms is out in Synthetic Biology today! In this study, took a deep dive into Modular Extracellular Sensor Architecture (MESA) design, identified several handles for substantially improving performance, and applied these findings to build next-gen receptors. We hope that these insights will help guide the use of MESA receptors for many applications and may also inform the design and refinement of other synthetic receptors. Congrats to Hailey, Patrick, Joe, Anthony, Taylor, Lauren, Everett, and Amy! Check out our paper here!
