This review discusses both recent advances and emerging general principles for using mammalian synthetic biology to build cell-based therapies that are safe and effective. Read more here.
This chapter summarizes key strategies and challenges associated with studying and harnessing EV-mediated transfer for therapeutic applications, while providing contemporary perspectives on how choices of systems design and analysis method may impact the efficacy of EV-based therapies and the interpretation of EV-based investigations. Read more here.
Kelly’s thesis research was profiled in a feature in Northwestern’s Alumni Magazine
Josh was selected to join the Scientific Executive Committee of GP-Write, a multinational synthetic biology project dedicated to realizing whole genome synthesis in order to understand, engineer and test living systems.
As part of former Vice President Joe Biden’s Cancer Moonshot Initiative, we received an award from NSF to work with fellow synthetic biologists at MIT to develop novel technologies for enabling cancer immunotherapy.