Synthetic biology: Sensing with modular receptors
Matthew Brenner, Jang Hwan Cho and Wilson W Wong
Sensing and responding to diverse extracellular signals is a crucial aspect of cellular decision-making that is currently lacking in the synthetic biology toolkit. The development of modular receptor platforms allows for the rewiring of cellular input-output relationships.
Image by Joshua Leonard and Kelly Schwarz, Northwestern University. Cell image by NIAID/NIH, used and modified under Creative Commons 2.0 license.
Congrats to Kelly, Nickey, and Taylor, whose paper was published today in Nature Chemical Biology! This paper is currently spotlighted on the homepage of NCB: http://www.nature.com/nchembio/index.html
Andrew’s new biosensor engineering paper, co-authored with former undergraduate mentees Neil and Austin, was published in ACS Synthetic Biology
Andy and Andrew’s paper was accepted for publication in ACS Synthetic Biology (a collaboration with our partners at the University of Warwick)
Michelle’s collaborative paper with Carol Hall at NC State was published in the Journal of Computational Chemistry.
Yishan, Michelle, and Brianne’s paper was on macrophage decision making in response to IL-10 was accepted for publication in Innate Immunity.